Neuroprotective 2-(2-phenylethyl)chromones of Imperata cylindrica.

نویسندگان

  • Jeong Seon Yoon
  • Mi Kyeong Lee
  • Sang Hyun Sung
  • Young Choong Kim
چکیده

Bioactivity-guided fractionation of the methanolic extract of the rhizomes of Imperata cylindrica afforded a new compound, 5-hydroxy-2-(2-phenylethyl)chromone (1), together with three known compounds, 5-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (2), flidersiachromone (3), and 5-hydroxy-2-styrylchromone (4). Among these four compounds, 1 and 2 showed significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells.

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عنوان ژورنال:
  • Journal of natural products

دوره 69 2  شماره 

صفحات  -

تاریخ انتشار 2006